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Bioprinting is a new application of ink jet or plotting technology in which biomaterials plus cells are deposited onto a substrate. The polymerization of the synthetic or natural polymers can be initiated by light, temperature, pH change or addition of ions. Our bioprinter "Bio Factory" (RegenHu, Villaz St-Pierre, Switzerland)  is currently equipped with three printing heads for printing of hydrogels containing cells. An additional printhead is used to dispense high viscous materials such as ceramic pastes.

BioPrinter and Laser  
Bioprinter "Bio Factory" from regenHU SA. The printer is equipped with three printheads for normal viscosites, one for high viscosities and a UV lamp. The system is also equipped with a 355 nm UV-Laser for photopolymerization.

For photo-polymerization of the hydrogels, the printer is equipped with a UV-lamp as well as a UV-laser with a wavelength of 355 nm. For temperature control, the cartridge and the printhead can be heated. The Bio Factory can dispense hydrogels in contact (extrusion printing) or non-contact mode (ink jet printing) depending on the viscosity of the material. The entire system is contained within a laminar flow hood so that the manufacture can be done in a sterile environment.

Needle inclusive valve for extrusion printing (left and middle) and a jetting valve for non-contact printing. The scale indicates 1 mm

The three-dimensional printing is facilitated via layer-by-layer build-up of the structures as it is shown in the video below.

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Tue Jun 27 10:59:15 CEST 2017
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